Sound propagation over uneven ground and irregular topography

The development of theoretical, computational, and experimental techniques for predicting the effects of irregular topography on long range sound propagation in the atmosphere is discussed. Irregular topography here is understood to imply a ground surface that (1) is not idealizable as being perfectly flat or (2) that is not idealizable as having a constant specific acoustic impedance. The study focuses on circumstances where the propagation is similar to what might be expected for noise from low-altitude air vehicles flying over suburban or rural terrain, such that rays from the source arrive at angles close to grazing incidence

A Data Fusion Technique to Detect Wireless Network Virtual Jamming Attacks

The file attached to this record is the author's final peer reviewed version. The Publisher's final version can be found by following the DOI link.Wireless communications are potentially exposed to jamming due to the openness of the medium and, in particular, to virtual jamming, which allows more energy-efficient attacks. In this paper we tackle the problem of virtual jamming attacks on IEEE 802.11 networks and present a data fusion solution for the detection of a type of virtual jamming attack (namely, NAV attacks), based on the real-time monitoring of a set of metrics. The detection performance is evaluated in a number of real scenarios

Project management of an integrated iron and steelworks during design, planning and construction

Much has been said, and many papers written, on the technical design problems associated with all branches of engineering involved in the building of a multi-million pound integrated steel plant. The object of this paper is not to add to their number, but rather to highlight the executive and management problems which arise in the course of the development and construction of this type of plant

Bystander B cells rapidly acquire antigen receptors from activated B cells by membrane transfer: a novel mechanism for enhancing specific antigen presentation

The B cell antigen receptor (BCR) efficiently facilitates the capture and processing of a specific antigen for presentation on MHC class II molecules to antigen specific CD4+ T cells (1). Despite this, the majority of B cells are only thought to play a limited role in CD4+ T cell activation since BCRs are clonotypically expressed. Here we show, however, that activated B cells can, both in vitro and in vivo, rapidly donate their BCR to bystander B cells, a process that is mediated by direct membrane transfer between adjacent B cells and is amplified by the interaction of the BCR with specific antigen. This results in a dramatic expansion in the number of antigen-binding B cells in vivo, with the transferred BCR endowing recipient B cells with the ability to present specific antigen to antigen-specific CD4+ T cells

Bound states in a quasi-two-dimensional Fermi gas

We consider the problem of N identical fermions of mass M and one distinguishable particle of mass m interacting via short-range interactions in a confined quasi-two-dimensional (quasi-2D) geometry. For N=2 and mass ratios M/m<13.6, we find non-Efimov trimers that smoothly evolve from 2D to 3D. In the limit of strong 2D confinement, we show that the energy of the N+1 system can be approximated by an effective two-channel model. We use this approximation to solve the 3+1 problem and we find that a bound tetramer can exist for mass ratios M/m as low as 5 for strong confinement, thus providing the first example of a universal, non-Efimov tetramer involving three identical fermions.Comment: 5 pages, 4 figure

Observation of an orbital interaction-induced Feshbach resonance in 173-Yb

We report on the experimental observation of a novel inter-orbital Feshbach resonance in ultracold 173-Yb atoms, which opens the possibility of tuning the interactions between the 1S0 and 3P0 metastable state, both possessing vanishing total electronic angular momentum. The resonance is observed at experimentally accessible magnetic field strengths and occurs universally for all hyperfine state combinations. We characterize the resonance in the bulk via inter-orbital cross-thermalization as well as in a three-dimensional lattice using high-resolution clock-line spectroscopy.Comment: 5 pages, 4 figure

Methionine sulfoximine resistance in Mycobacterium tuberculosis is due to a single nucleotide deletion resulting in increased expression of the major glutamine synthetase, GlnA1

We investigated the effect of methionine sulfoximine (MetSox), a potent inhibitor of glutamine synthetase, on Mycobacterium tuberculosis. M. tuberculosis encodes four glutamine synthetases, of which MetSox targets the type I enzyme encoded by glnA1. Trancriptional profiling revealed that glutamate synthetase (gltB) and a type II glutamine synthetase (glnA3) were induced after exposure to MetSox. In addition, we observed a high rate (10−5) of spontaneous resistance to MetSox. All resistant strains had a single-nucleotide deletion in the 5’ region of glnA1, and Western analysis revealed that GlnA1 expression was increased in resistant as compared with sensitive strains. These data show that M. tuberculosis can respond to the effect of MetSox inhibition either by up-regulation of GlnA3 or by GlnA1. The high frequency of resistance suggests that MetSox and other compounds specifically targeting GlnA1 are not likely to become successful anti-mycobacterial agents

Shuttle-launch triangular space station

A triangular space station deployable in orbit is described. The framework is comprized of three trusses, formed of a pair of generally planar faces consistine of foldable struts. The struts expand and lock into rigid structural engagement forming a repetition of equilater triangles and nonfolding diagonal struts interconnecting the two faces. The struts are joined together by node fittings. The framework can be packaged into a size and configuration transportable by a space shuttle. When deployed, the framework provides a large work/construction area and ample planar surface area for solar panels and thermal radiators. A plurity of modules are secured to the framework and then joined by tunnels to make an interconnected modular display. Thruster units for the space station orientation and altitude maintenance are provided